Research Core Facilities
In support of its research and educational activities, Dana-Farber Cancer Institute has developed and centrally maintains a variety of core facilities and service functions to support its research and educational activities, including:
Animal Research Facility
The facility provides services and resources needed by investigators to accomplish their animal research objectives, provides training in laboratory animal care and use to staff, students and researchers, and, in conjunction with DFCI Environmental Health and Safety, monitors the safety of investigators, technicians and all personnel with laboratory animal contact.
Location: Smith 11 & 12 and Mayer Building
Contact E-mail: barbara_smith1@dfci.harvard.edu
Baruj Benacerraf Library
The Baruj Benacerraf Library provides journals and books, photocopying, interlibrary loans, database searching and training in database searching, as well as public access to computers. The library is open from 9 a.m. to 5 p.m., Monday through Friday.
Location: Smith 314
Contact E-mail: Christine_Fleuriel@dfci.harvard.edu
Biohazard Containment Suite
This core provides technical support in the preparation and propagation of viral stock and cell lines. It also provides technical support in phenotypic characterization of virus variants.
Location: Jimmy Fund 7
Contact E-mail: dana_gabuzda@dfci.harvard.edu
Biostatistics & Computational Biology Core
Biostatistics provides biostatistical expertise for the planning, conduct, analysis, reporting, and grant preparation of clinical, laboratory, and population-based studies.
Location: CLSB, 11th Floor
Contact E-mail: Beverly Lewis, lewis@jimmy.harvard.edu
The Connell and O'Reilly Families Cell Manipulation Core
The Connell and O'Reilly Families Cell Manipulation Core provides cell processing for patients enrolled in clinical research protocols. A variety of innovative cell manipulation techniques are currently available, including processing of hematopoietic stem cells, preparation of tumor vaccines, and generation of T cells for adoptive immunotherapy.
Location: Dana 530
Contact E-mail: Jerome_Ritz@dfci.harvard.edu
Flow Cytometry Core Lab
The Flow Cytometry Core supports Research at Dana-Farber. Our services include three high-speed cell sorters, four tabletop analyzers that can be used 24/7, and a BioPlex 200. For more information, please visit our Web site at flowlab.dfci.harvard.edu.
Location: Jimmy Fund 415
Contact E-mail: Peter_Schow@dfci.harvard.edu
Health Communication
The Health Communication Core (HCC) brings art to your science by offering DF/HCC researchers a wide range of services that help them develop and deliver their messages in a way that is engaging, attractive, and effective.
Location: LW, 7th Floor
Contact E-mail: vish_viswanath@dfci.harvard.edu
Medical Arts
Medical Arts provides complete computer and custom graphics and photography services, including all needs for scientific publications and presentations, color and black and white prints, slides, full posters and titles, brochures, flyers, adds, and special events photography.
Location: OS374
Contact E-mail: Minou_Modabber@dfci.harvard.edu
Microarray Core Facility
Starting with RNA provided by investigators, the facility carries out expression profiling using oligonucleotide microarrays. Genome-wide SNP analysis and resequencing analysis using oligonnucleotide microarrays are also services of the laboratory.
Location: BA464
Contact E-mail: Edward_Fox@dfci.harvard.edu
Molecular Biology Core Facilities
The Molecular Biology Core Facilities offers a full suite of molecular biology services to the Institute as well as the surrounding Harvard Medical School. These services include automated DNA sequencing, DNA and peptide synthesis, protein sequencing, amino acid analysis, BIAcore protein ligand assays, and mass spectrometry.
Location: 21-27 Burlington Ave, 4th floor
Contact E-mail: Paul_Morrison@dfci.harvard.edu
Molecular Biology Core Facilities Web site
Monoclonal Antibody Core
The Monoclonal Antibody Core was created to provide consistent, economical, and high quality protein and antibody generation and production, as well as to provide antibody-related products and services to support basic research and clinical projects.
Location: 21-27 Burlington Ave., 4th floor
Contact Core Director: James_DeCaprio@dfci.harvard.edu
Contact Co-Director: Laura_Corral@dfci.harvard.edu
DF/HCC Monoclonal Antibody Web site
RNA Interference (RNAi) Screening Facility
The facility provides reagents, equipment, and expertise to design, optimiz,e and perform cell-based, arrayed lentiviral RNAi screens.
Location: Smith 8
Contact E-mail: Soyoung_Kim@dfci.harvard.edu
The Shannon McCormack Molecular Diagnostics Laboratory
The Shannon McCormack Molecular Diagnostics Laboratory provides miRNA expression profiling and human cell line identity verification, as well as support for clinical research studies that include specimen processing and tracking, DNA sequencing, microsatellite and SNP analyses, quantitative PCR, and other methods used to analyze genes that may be involved in the etiology of cancer.
Shannon McCormack Molecular Diagnostics Laboratory Web site
Location: 21-27 Burlington Ave, 4th floor
Contact E-mail: Edward_Fox@dfci.harvard.edu
Transgenic Mouse Core
The core provides holding, breeding, and cryopreserving of mouse models as well as technical support and expertise in the area of transgenic and gene targeted mouse models.
Location: Mayer 484 and Smith 1225
Contact E-mail: james_horner@dfci.harvard.edu
Tumor Imaging Metrics Core
The core provides standardized structural and functional radiological measurements (e.g. RECIST, WHO, Cheson, SUV) for CT, MR and PET imaging modalities to evaluate tumor response for DF/HCC clinical trials.
Location: MGH, BWH, Dana Lobby 101
Contact E-mail: Gordon Harris, Harris.Gordon@mgh.harvard.edu
